Review Article

Association between Toll-Like Receptor 4 Polymorphisms and Systemic Lupus Erythematosus Susceptibility: A Meta-Analysis

Table 3

Meta-analysis of TLR4 polymorphism with the risk of SLE.

PolymorphismGenetic modelTest of associationTest of heterogeneity
OR95% CIModel

D299GDominant1.310.96, 1.800.09Fixed0.0%0.432
Recessive2.180.65, 7.240.21Fixed53.3%0.143
Allele1.300.98, 1.730.07Fixed16.6%0.301

T399IDominant1.180.85, 1.640.33Fixed0.0%0.710
Recessive2.520.66, 9.630.18Fixed62.7%0.102
Allele1.200.89, 1.620.24Fixed0.0%0.538