Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2016, Article ID 7893961, 8 pages
http://dx.doi.org/10.1155/2016/7893961
Research Article

Sperm DNA Fragmentation Index and Hyaluronan Binding Ability in Men from Infertile Couples and Men with Testicular Germ Cell Tumor

1Department of Andrology and Reproductive Endocrinology, Medical University of Lodz, Lodz, Poland
2II Clinic of Urology, Medical University of Lodz, Lodz, Poland
3Infertility Clinic, Salve Medica, Lodz, Poland

Received 5 October 2016; Accepted 26 October 2016

Academic Editor: Janusz Blasiak

Copyright © 2016 Katarzyna Marchlewska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. L. Conti and M. L. Eisenberg, “Paternal aging and increased risk of congenital disease, psychiatric disorders, and cancer,” Asian Journal of Andrology, vol. 18, no. 3, pp. 420–424, 2016. View at Publisher · View at Google Scholar
  2. K. Plastira, P. Msaouel, R. Angelopoulou et al., “The effects of age on DNA fragmentation, chromatin packaging and conventional semen parameters in spermatozoa of oligoasthenoteratozoospermic patients,” Journal of Assisted Reproduction and Genetics, vol. 24, no. 10, pp. 437–443, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Giwercman and Y. L. Giwercman, “Epidemiology of male reproductive disorders,” in Endotext, L. J. De Groot, G. Chrousos, K. Dungan et al., Eds., MDText.com, Inc., South Dartmouth, Mass, USA, 2000. View at Google Scholar
  4. S. C. Esteves and A. Agarwal, “Novel concepts in male infertility,” International Brazilian Journal of Urology, vol. 37, no. 1, pp. 5–15, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Henkel, E. Kierspel, T. Stalf et al., “Effect of reactive oxygen species produced by spermatozoa and leukocytes on sperm functions in non-leukocytospermic patients,” Fertility and Sterility, vol. 83, no. 3, pp. 635–642, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. L. Tamburrino, S. Marchiani, M. Montoya et al., “Mechanisms and clinical correlates of sperm DNA damage,” Asian Journal of Andrology, vol. 14, no. 1, pp. 24–31, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. F. Leduc, V. Maquennehan, G. B. Nkoma, and G. Boissonneault, “DNA damage response during chromatin remodeling in elongating spermatids of mice,” Biology of Reproduction, vol. 78, no. 2, pp. 324–332, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. J. R. Spermon, L. A. L. M. Kiemeney, E. J. H. Meuleman, L. Ramos, A. M. M. Wetzels, and J. A. Witjes, “Fertility in men with testicular germ cell tumors,” Fertility and Sterility, vol. 79, no. 3, pp. 1543–1549, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Albers, W. Albrecht, F. Algaba et al., “EAU guidelines on testicular cancer: 2011 update,” European Urology, vol. 60, no. 2, pp. 304–319, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Smit, N. J. van Casteren, M. F. Wildhagen, J. C. Romijn, and G. R. Dohle, “Sperm DNA integrity in cancer patients before and after cytotoxic treatment,” Human Reproduction, vol. 25, no. 8, pp. 1877–1883, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. M. S. Kupka, A. P. Ferraretti, J. de Mouzon et al., “Assisted reproductive technology in Europe, 2010: results generated from European registers by ESHRE,” Human Reproduction (Oxford, England), vol. 29, no. 10, pp. 2099–2113, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. D. S. Irvine, J. P. Twigg, E. L. Gordon, N. Fulton, P. A. Milne, and R. J. Aitken, “DNA integrity in human spermatozoa: relationships with semen quality,” Journal of Andrology, vol. 21, no. 1, pp. 33–44, 2000. View at Google Scholar · View at Scopus
  13. A. Ahmadi and S.-C. Ng, “Developmental capacity of damaged spermatozoa,” Human Reproduction, vol. 14, no. 9, pp. 2279–2285, 1999. View at Publisher · View at Google Scholar · View at Scopus
  14. J. L. Fernández, L. Muriel, V. Goyanes et al., “Simple determination of human sperm DNA fragmentation with an improved sperm chromatin dispersion test,” Fertility and Sterility, vol. 84, no. 4, pp. 833–842, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. B. L. Sailer, L. K. Jost, and D. P. Evenson, “Mammalian sperm DNA susceptibility to in situ denaturation associated with the presence of DNA strand breaks as measured by the terminal deoxynucleotidyl transferase assay,” Journal of Andrology, vol. 16, no. 1, pp. 80–87, 1995. View at Google Scholar · View at Scopus
  16. I. D. Morris, S. Ilott, L. Dixon, and D. R. Brison, “The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development,” Human Reproduction, vol. 17, no. 4, pp. 990–998, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. D. P. Evenson, “The Sperm Chromatin Structure Assay (SCSA) and other sperm DNA fragmentation tests for evaluation of sperm nuclear DNA integrity as related to fertility,” Animal Reproduction Science, vol. 169, pp. 56–75, 2016. View at Publisher · View at Google Scholar
  18. K. R. Chohan, J. T. Griffin, M. Lafromboise, C. J. De Jonge, and D. T. Carrell, “Comparison of chromatin assays for DNA fragmentation evaluation in human sperm,” Journal of Andrology, vol. 27, no. 1, pp. 53–59, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. K. A. Redgrove, A. L. Anderson, E. A. McLaughlin, M. K. O'Bryan, R. J. Aitken, and B. Nixon, “Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition,” Molecular Human Reproduction, vol. 19, no. 3, pp. 120–135, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. K. C. Worrilow, S. Eid, D. Woodhouse et al., “Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes-multicenter, double-blinded and randomized controlled trial,” Human Reproduction, vol. 28, no. 2, pp. 306–314, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. G. Huszar, C. C. Ozenci, S. Cayli, Z. Zavaczki, E. Hansch, and L. Vigue, “Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status,” Fertility and Sterility, vol. 79, no. 3, supplement, pp. 1616–1624, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. G. Huszar, A. Jakab, D. Sakkas et al., “Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspects,” Reproductive BioMedicine Online, vol. 14, no. 5, pp. 650–663, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. M. H. Nasr-Esfahani, S. Razavi, A. A. Vahdati, F. Fathi, and M. Tavalaee, “Evaluation of sperm selection procedure based on hyaluronic acid binding ability on ICSI outcome,” Journal of Assisted Reproduction and Genetics, vol. 25, no. 5, pp. 197–203, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Cayli, D. Sakkas, L. Vigue, R. Demir, and G. Huszar, “Cellular maturity and apoptosis in human sperm: creatine kinase, caspase-3 and Bcl-XL levels in mature and diminished maturity sperm,” Molecular Human Reproduction, vol. 10, no. 5, pp. 365–372, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. W.-Y. Son, S.-H. Hwang, C.-T. Han, J.-H. Lee, S. Kim, and Y. C. Kim, “Specific expression of heat shock protein HspA2 in human male germ cells,” Molecular Human Reproduction, vol. 5, no. 12, pp. 1122–1126, 1999. View at Publisher · View at Google Scholar · View at Scopus
  26. WHO, WHO Laboratory Manual for the Examination and Processing of Human Semen, vol. 5, WHO, Geneva, Switzerland, 2010.
  27. D. Evenson and R. Wixon, “Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay,” Reproductive BioMedicine Online, vol. 12, no. 4, pp. 466–472, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. C. O'Flaherty, F. Vaisheva, B. F. Hales, P. Chan, and B. Robaire, “Characterization of sperm chromatin quality in testicular cancer and Hodgkin's lymphoma patients prior to chemotherapy,” Human Reproduction, vol. 23, no. 5, pp. 1044–1052, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. D. Paoli, M. Gallo, F. Rizzo et al., “Testicular cancer and sperm DNA damage: short- and long-term effects of antineoplastic treatment,” Andrology, vol. 3, no. 1, pp. 122–128, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. J. R. Spermon, L. Ramos, A. M. M. Wetzels et al., “Sperm integrity pre- and post-chemotherapy in men with testicular germ cell cancer,” Human Reproduction, vol. 21, no. 7, pp. 1781–1786, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. O. Ståhl, J. Eberhard, E. Cavallin-Ståhl et al., “Sperm DNA integrity in cancer patients: the effect of disease and treatment,” International Journal of Andrology, vol. 32, no. 6, pp. 695–703, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. C. O'Flaherty, B. F. Hales, P. Chan, and B. Robaire, “Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity,” Fertility and Sterility, vol. 94, no. 4, pp. 1374–1379, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. G. R. Dohle, “Male infertility in cancer patients: review of the literature,” International Journal of Urology, vol. 17, no. 4, pp. 327–331, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Erenpreiss, M. Spano, J. Erenpreisa, M. Bungum, and A. Giwercman, “Sperm chromatin structure and male fertility: biological and clinical aspects,” Asian Journal of Andrology, vol. 8, no. 1, pp. 11–29, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. J. Zhao, Q. Zhang, Y. Wang, and Y. Li, “Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: a systematic review and meta-analysis,” Fertility and Sterility, vol. 102, no. 4, pp. 998.e8–1005.e8, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. O. Ståhl, J. Eberhard, K. Jepson et al., “Sperm DNA integrity in testicular cancer patients,” Human Reproduction, vol. 21, no. 12, pp. 3199–3205, 2006. View at Publisher · View at Google Scholar · View at Scopus
  37. I. Vakalopoulos, P. Dimou, I. Anagnostou, and T. Zeginiadou, “Impact of cancer and cancer treatment on male fertility,” Hormones (Athens), vol. 14, no. 4, pp. 579–589, 2015. View at Publisher · View at Google Scholar · View at Scopus
  38. Z. Molnar, A. Mokanszki, Z. K. Bazsane et al., “Sperm concentration, hyaluronic acid-binding capacity, aneuploidy and persistent histones in testicular cancer,” Human Reproduction, vol. 29, no. 9, pp. 1866–1874, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. L. Parmegiani, G. E. Cognigni, and M. Filicori, “Risks in injecting hyaluronic acid non-bound spermatozoa,” Reproductive BioMedicine Online, vol. 20, no. 3, pp. 437–439, 2010. View at Publisher · View at Google Scholar · View at Scopus
  40. A. Yagci, W. Murk, J. Stronk, and G. Huszar, “Spermatozoa bound to solid state hyaluronic acid show chromatin structure with high DNA chain integrity: an acridine orange fluorescence study,” Journal of Andrology, vol. 31, no. 6, pp. 566–572, 2010. View at Publisher · View at Google Scholar · View at Scopus
  41. T. E. Schmid, B. Eskenazi, A. Baumgartner et al., “The effects of male age on sperm DNA damage in healthy non-smokers,” Human Reproduction, vol. 22, no. 1, pp. 180–187, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. A. J. Wyrobek, B. Eskenazi, S. Young et al., “Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 25, pp. 9601–9606, 2006. View at Publisher · View at Google Scholar · View at Scopus
  43. B. Ozkosem, S. I. Feinstein, A. B. Fisher, and C. O'Flaherty, “Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice,” Redox Biology, vol. 5, pp. 15–23, 2015. View at Publisher · View at Google Scholar · View at Scopus