Cytotoxicity of Titanate-Calcium Complexes to MC3T3 Osteoblast-Like Cells

Figure 1

MC3T3 osteoblast metabolic activity (measured by CellTiter-Blue® (CTB)) after in vitro exposure to monosodium titanates (MST) at (a) 5,000 cells/cm² or (b) 30,000 cells/cm² for 24 or 72 h. Metabolic activity was normalized to controls without MST (denoted by horizontal dashed line). Lower cell plating densities and increased time of exposure led to depressed cell activity. Uppercase letters (A, B, and C) indicate statistical differences (Tukey pairwise comparisons, , and ).

(a)

(b)