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BioMed Research International
Volume 2016, Article ID 7926961, 7 pages
http://dx.doi.org/10.1155/2016/7926961
Research Article

Cytotoxicity and Initial Biocompatibility of Endodontic Biomaterials (MTA and Biodentine) Used as Root-End Filling Materials

1Basic Sciences Laboratory, Faculty of Dentistry, San Luis Potosi University, 78290 San Luis Potosí, SLP, Mexico
2Endodontics Posgraduated Program, Faculty of Dentistry, San Luis Potosi University, 78290 San Luis Potosí, SLP, Mexico

Received 24 May 2016; Revised 23 June 2016; Accepted 13 July 2016

Academic Editor: Bugra Ozen

Copyright © 2016 Diana María Escobar-García et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Asgary, S. Shahabi, T. Jafarzadeh, S. Amini, and S. Kheirieh, “The properties of a new endodontic material,” Journal of Endodontics, vol. 34, no. 8, pp. 990–993, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Holliday and A. Alani, “Traditional and contemporary techniques for optimizing root canal irrigation,” Dental Update, vol. 41, no. 1, pp. 51–52, 2014. View at Google Scholar
  3. H. A. Balto, “Attachment and morphological behavior of human periodontal ligament fibroblasts to mineral trioxide aggregate: a scanning electron microscope study,” Journal of Endodontics, vol. 30, no. 1, pp. 25–29, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. H. W. Roberts, J. M. Toth, D. W. Berzins, and D. G. Charlton, “Mineral trioxide aggregate material use in endodontic treatment: a review of the literature,” Dental Materials, vol. 24, no. 2, pp. 149–164, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. N. S. Shojaee, S. Sahebi, E. Karami, and F. Sobhnamayan, “Solubility of two root-end filling materials over different time periods in synthetic tissue fluid: a comparative study,” Journal of Dentistry (Shiraz, Iran), vol. 16, no. 3, pp. 189–194, 2015. View at Google Scholar
  6. M. Song, T. S. Yoon, S. Y. Kim, and E. Kim, “Cytotoxicity of newly developed pozzolan cement and other root-end filling materials on human periodontal ligament cell,” Restorative Dentistry & Endodontics, vol. 39, no. 1, pp. 39–44, 2014. View at Publisher · View at Google Scholar
  7. Q. Zhu, R. Haglund, K. E. Safavi, and L. S. Spangberg, “Adhesion of human osteoblasts on root-end filling materials,” Journal of Endodontics, vol. 26, no. 7, pp. 404–406, 2000. View at Publisher · View at Google Scholar
  8. E. J. Silva, P. M. Senna, G. De-Deus, and A. A. Zaia, “Cytocompatibility of biodentine using a three-dimensional cell culture model,” International Endodontic Journal, vol. 49, no. 6, pp. 574–580, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Bidar, J. Tavakkol Afshari, and F. Shahrami, “Evaluation of adhesion and morphology of human osteoblasts to white MTA and Portland cement,” Iranian Endodontic Journal, vol. 2, no. 3, pp. 87–90, 2007. View at Google Scholar
  10. A. Nowicka, M. Lipski, M. Parafiniuk et al., “Response of human dental pulp capped with biodentine and mineral trioxide aggregate,” Journal of Endodontics, vol. 39, no. 6, pp. 743–747, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. Z. Luo, M. R. Kohli, Q. Yu, S. Kim, T. Qu, and W.-X. He, “Biodentine induces human dental pulp stem cell differentiation through mitogen-activated protein kinase and calcium-/calmodulin-dependent protein kinase II pathways,” Journal of Endodontics, vol. 40, no. 7, pp. 937–942, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. Ö. Malkondu, M. K. Kazandağ, and E. Kazazoğlu, “A review on biodentine, a contemporary dentine replacement and repair material,” BioMed Research International, vol. 2014, Article ID 160951, 10 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. Q. Wang, X. Yang, M. Ren et al., “Effect of chitosan/type I collagen/gelatin composites in biocompatibility and nerve repair,” Neural Regeneration Research, vol. 7, no. 15, pp. 1179–1184, 2012. View at Google Scholar · View at Scopus
  14. G. R. Owen, D. O. Meredith, I. Gwynn, and R. G. Richards, “Focal adhesion quantification a new assay of material biocompatibility?” European Cells & Materials, vol. 23, no. 9, pp. 85–96, 2005. View at Google Scholar
  15. S. Margunato, P. N. Taşli, S. Aydin, M. Karapinar Kazandağ, and F. Şahin, “In vitro evaluation of ProRoot MTA, biodentine, and MM-MTA on human Alveolar bone marrow stem cells in terms of biocompatibility and mineralization,” Journal of Endodontics, vol. 41, no. 10, pp. 1646–1652, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Widbiller, S. R. Lindner, W. Buchalla et al., “Three-dimensional culture of dental pulp stem cells in direct contact to tricalcium silicate cements,” Clinical Oral Investigations, vol. 20, no. 2, pp. 237–246, 2016. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Khedmat, S. Dehghan, and J. Hadjati, “In vitro cytotoxicity of four calcium silicate-based endodontic cements on human monocytes, a colorimetric MTT assay,” Restorative Dentistry & Endodontics, vol. 39, no. 3, pp. 149–154, 2014. View at Google Scholar
  18. C. M. Corral Nuñez, H. J. Bosomworth, C. Field, J. M. Whitworth, and R. A. Valentine, “Biodentine and mineral trioxide aggregate induce similar cellular responses in a fibroblast cell line,” Journal of Endodontics, vol. 40, no. 3, pp. 406–411, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. M. O. Daltoé, F. W. Paula-Silva, L. H. Faccioli, P. M. Gatón-Hernández, A. De Rossi, and L. A. Bezerra Silva, “Expression of mineralization markers during pulp response to biodentine and mineral trioxide aggregate,” Journal of Endodontics, vol. 42, no. 4, pp. 596–603, 2016. View at Publisher · View at Google Scholar
  20. C. Poggio, C. R. Arciola, R. Beltrami et al., “Cytocompatibility and antibacterial properties of capping materials,” The Scientific World Journal, vol. 2014, Article ID 181945, 10 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Poggio, M. Ceci, R. Beltrami, A. Dagna, M. Colombo, and M. Chiesa, “Biocompatibility of a new pulp capping cement,” Annali di Stomatologia, vol. 5, no. 2, pp. 69–76, 2014. View at Publisher · View at Google Scholar
  22. B. M. Gumbiner, “Cell adhesion: the molecular basis of tissue architecture and morphogenesis,” Cell, vol. 84, no. 3, pp. 345–357, 1996. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Rakshit and S. Sivasankar, “Biomechanics of cell adhesion: how force regulates the lifetime of adhesive bonds at the single molecule level,” Physical Chemistry Chemical Physics, vol. 16, no. 6, pp. 2211–2223, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Fayazi, S. N. Ostad, and H. Razmi, “Effect of ProRoot MTA, Portland cement, and amalgam on the expression of fibronectin, collagen I, and TGFβ by human periodontal ligament fibroblasts in vitro,” Indian Journal of Dental Research, vol. 22, no. 2, pp. 190–194, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. W. H. Goldmann, V. Auernheimer, I. Thievessen, and B. Fabry, “Vinculin, cell mechanics and tumour cell invasion,” Cell Biology International, vol. 37, no. 5, pp. 397–405, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. I. Elloumi-Hannachi, J. R. García, A. Shekeran, and A. J. García, “Contributions of the integrin β1 tail to cell adhesive forces,” Experimental Cell Research, vol. 332, no. 2, pp. 212–222, 2015. View at Publisher · View at Google Scholar · View at Scopus
  27. P. M. Thompson, C. E. Tolbert, and S. L. Campbell, “Vinculin and metavinculin: oligomerization and interactions with F-actin,” FEBS Letters, vol. 587, no. 8, pp. 1220–1229, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. J.-Y. Jo, S.-I. Jeong, Y.-M. Shin et al., “Sequential delivery of BMP-2 and BMP-7 for bone regeneration using a heparinized collagen membrane,” International Journal of Oral and Maxillofacial Surgery, vol. 44, no. 7, pp. 921–928, 2015. View at Publisher · View at Google Scholar · View at Scopus