The HPV16 E7 Oncoprotein Disrupts Dendritic Cell Function and Induces the Systemic Expansion of CD11b⁺Gr1⁺ Cells in a Transgenic Mouse Model

Figure 1

CD207⁺ cells detected in mouse epidermis. (a) Epidermal sheets of nontransgenic (NT) and K14E7 mice were stained with anti-CD207 antibody, and cell nuclei were counterstained with DAPI. Magnification, 63x. Scale bar = 30 μm. (b) Numbers of CD207⁺ cells per field and (c) dendrites on CD207⁺ cells were counted using confocal microscopy. Significant differences are indicated with asterisks: .

(a)

(b)

(c)