The HPV16 E7 Oncoprotein Disrupts Dendritic Cell Function and Induces the Systemic Expansion of CD11b+Gr1+ Cells in a Transgenic Mouse Model
MCP1, INF-γ, IL-6, and S100A9 expression levels in K14E7 mouse skin. (a) MCP1, INF-γ, and IL-6 protein levels in skin cells from nontransgenic (NT) and K14E7 mice were evaluated by cytometric bead array using flow cytometry ( mice per experimental group). (b) Expression of S100A9 in NT and K14E7 mouse skin as detected by Western blotting; beta-actin expression was used as a loading control. Experiments were performed in duplicate at least 2 times. Significant differences are indicated with asterisks: , .
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.