Research Article

Predictive Significance of Serum Level of Vascular Endothelial Growth Factor in Gastric Cancer Patients

Table 1

Correlation of serum VEGF with clinical indicators in patients with gastric cancer (median (IQR)).

ParametersNumberVEGF (pg/mL) value

Gender
 Male112 (72.7%)151.686 (143.640)0.942
 Female42 (27.3%)134.643 (154.517)
Age
 ≤6070 (45.5%)130.314 (140.753)0.056
 >6084 (54.5%)163.089 (163.860)
Differentiation degree
 Low92 (59.7%)171.181 (158.886)0.012
 Moderate58 (37.7%)116.824 (104.379)
 High4 (2.6%)163.360 (179.338)
Clinical stages
 I+II84 (54.5%)121.702 (138.479)0.004
 III+IV70 (45.5%)173.823 (146.996)
Depth of infiltration
 T1+T259 (38.3%)110.770 (99.111)0.004
 T3+T495 (61.7%)171.692 (158.016)
Lymph node metastasis
 No60 (39.0%)122.274 (112.414)0.036
 Yes94 (61%)171.669 (149.365)
Distant metastasis
 No138 (89.6%)145.812 (148.228)0.854
 Yes16 (10.4%)153.702 (113.545)
Lauren
 Intestinal64 (41.6%)154.309 (149.211)0.651
 Diffuse43 (27.9%)135.712 (145.44)
 Mixed46 (29.9%)155.912 (171.842)
 Unknown1 (0.6%)149.933
HER2
 Negative70 (45.5%)149.126 (137.971)0.397
 Positive74 (48.1%)137.630 (155.948)
 Unknown10 (6.4%)151.686 (105.018)
EGFR
 Negative7 (4.5%)99.352 (402.412)0.708
 Positive127 (82.5%)140.213 (143.821)
 Unknown20 (13.0%)156.699 (108.166)
Tumor size
 ≤4 cm89 (57.8%)129.478 (141.868)0.028
 >4 cm49 (31.8%)169.255 (155.814)
 Unknown16 (10.4%)130.409 (120.659)

 Total154 (100%)