¹²⁵I Seeds Radiation Induces Paraptosis-Like Cell Death via PI3K/AKT Signaling Pathway in HCT116 Cells

Figure 9

Ly294002 inhibited the paraptosis induced by ¹²⁵I seeds radiation. HCT116 cells were exposed to ¹²⁵I seeds radiation alone or in combination with Ly294002 (10 μM). The morphology and structure of HCT116 cells were detected and calculated under light microscopy. (a) The representative confocal microscopy images are shown. (b) The percentage of vacuolar cell was quantified. (c) Cell viability of HCT116 cells was quantified by trypan blue exclusion. Means ± SD of triplicates are shown. .

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