Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice

Figure 2

No abnormal behavioral performance was observed in younger APP/PS1 mice (3 months old). There is no significant difference between WT and APP/PS1 mice at 3 months of age on the spontaneous alternation test in Y Maze (a). Total arm entrances showed no significant difference between WT and APP/PS1 mice at 3 months of age in Y maze test (b). Escape latency of hidden platform test in the 3-month-old WT and APP/PS1 mice (c). , each group. Data are expressed as means ± SEM.

(a)

(b)

(c)