Renal Ischemia/Reperfusion Injury in Diabetic Rats: The Role of Local Ischemic Preconditioning

<div>Representative kidney sections belong to (a) nondiabetic sham group, (b) diabetic sham group, (c1 and c2) diabetic ischemia-reperfusion (diabetic IR) group, and (d1 and d2) diabetic IR + LIPC group, respectively. Mononuclear infiltrations marked with black arrow (<svg height="6.27169pt" id="M65" style="vertical-align:-0.04980993pt" version="1.1" viewbox="-0.0498162 -6.22188 16.9064 6.27169" width="16.9064pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,2.179,0)"><path d="M901 255C861 290 790 361 716 442L694 427L796 280H69V230H796L694 83L716 68C790 149 861 220 901 255Z" id="g117-148"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="954" vert-adv-y="954"></glyph.data></g></svg>), hyalin substance deposition marked with white arrow with black edges (<svg height="7.35473pt" id="M66" style="vertical-align:-0.3499303pt" version="1.1" viewbox="-0.0498162 -7.0048 12.5482 7.35473" width="12.5482pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M901 255C852 301 765 395 674 502L652 487L727 373H69V323H759L804 255L760 188H69V138H727L652 23L674 8C765 115 852 209 901 255Z" id="g117-156"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="954" vert-adv-y="954"></glyph.data></g></svg>), and erythrocyte extravasations marked with (★). In micrographs proximal tubules, distal tubules and renal glomerulus are shown with (P), (D), and (G), respectively.</div>

BioMed Research International

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Figure 2: Renal Ischemia/Reperfusion Injury in Diabetic Rats: The Role of Local Ischemic Preconditioning 