Renal Ischemia/Reperfusion Injury in Diabetic Rats: The Role of Local Ischemic Preconditioning

Table 3

Biochemical data of the groups.

Groups	BUN	Cr	NGAL
Group I (nondiabetic sham); ()	49.83 ± 21.80; 44.20; 31.90–95.60	0.46 ± 0.18; 0.44; 0.27–0.80	446.43 ± 179.17; 386.00; 314.00–839.00
Group II (diabetic sham); ()	68.52 ± 15.07; 72.20; 39.30–83.50	0.43 ± 0.21; 0.39; 0.24–0.82	350.17 ± 35.62; 352.5; 295.00–395.00
Group III (diabetic IR); ()	79.62 ± 14.93; 78.20; 62.10–101.70	0.62 ± 0.20; 0.66; 0.29–0.83	891.17 ± 1308.03; 363.50; 296.00–3560.00
Group IV (diabetic IR + LIPC); ()	84.68 ± 16.79; 89.75; 52.00–96.80	0.81 ± 0.80; 0.81; 0.69–0.91	1107.40 ± 1294.21; 412; 397.00–3385.00
values
	0.086	0.567	0.153
	0.022	0.153	0.568
	0.032	0.010	0.167
	0.423	0.128	0.423
	0.037	0.016	0.006
	0.423	0.065	0.201

Group I: nondiabetic sham, Group II: diabetic sham, Group III (diabetic IR): renal ischemia/reperfusion injury in diabetic rats group, Group IV (diabetic IR + DIPC): renal ischemia/reperfusion injury in diabetic rats group and local ischemia preconditioning, BUN: blood urea nitrogen, and serum NGAL: Cr: blood creatinine level, Mann-Whitney test was conducted to compare two independent groups. Values are mean ± 1 SD, median, minimum, and maximum.
: comparison of nondiabetic sham and diabetic sham.
: comparison of nondiabetic sham and diabetic IR.
: comparison of nondiabetic sham and diabetic IR + LIPC.
: comparison of diabetic sham and diabetic IR.
: comparison of diabetic sham and diabetic IR + LIPC.
: comparison of diabetic IR and diabetic IR + LIPC.