Review Article

HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases

Table 4

Changes in expression of immune-related genes in response to HDAC inhibition.

MCP1 (monocyte chemotactic protein 1)[105]
MIP-1a (macrophage inflammatory protein 1a)[105]
CD154[106, 107]
IFN-γ[49, 106, 107]
NF-B[103]
NKG2D[108, 109]
PD-L1 [110]
MHC[103, 111114]
IL-10[106, 107, 115117]
Antigen processing proteins[113, 118]
IL-1β[49, 115]
IL-6[115]
IL-12[49]
TNF-[49]