Tricholoma matsutake Aqueous Extract Induces Hepatocellular Carcinoma Cell Apoptosis via Caspase-Dependent Mitochondrial Pathway

Figure 2

TM induced apoptosis in HepG2 and SMMC-7721 cells. (a) TM significantly enhanced the apoptotic rate in HepG2 and SMMC-7721 cells after 12 h incubation analyzing via flow cytometry (). (b) TM enhanced caspase-3, caspase-8, and caspase-9 activation in HepG2 and SMMC-7721 cells after 24 h exposure. Data are expressed as a percentage of that from corresponding control group and the means ± SD (). , , and versus control cells.

(a)

(b)