Research Article

Epidemic Profile of Maternal Syphilis in China in 2013

Table 2

Clinical characteristics of pregnant women with syphilis infection in China in 2013, by region.

Characteristic TotalRegion value
EasternCentral Western

History of syphilis infection
 Yes2910 (18.3%)1537 (23.2%)566 (14.9%)807 (14.8%)<0.001
 No12974 (81.7%)5082 (76.8%)3232 (85.1%)4660 (85.2%)
Maternal syphilis stage
 Latent syphilis10742 (67.6%)4751 (71.8%)2193 (57.7%)3798 (69.5%)<0.001
 Primary syphilis981 (6.2%)421 (6.4%)234 (6.2%)326 (6.0%)
 Secondary syphilis158 (1.0%)81 (1.2%)48 (1.3%)29 (0.5%)
 Tertiary syphilis73 (0.5%)39 (0.6%)17 (0.4%)17 (0.3%)
 Unknown3930 (24.7%)1327 (20.0%)1306 (34.4%)1297 (23.7%)
Period of maternal syphilis detection
 During pregnancy8829 (55.6%)4136 (62.5%)1728 (45.5%)2965 (54.2%)<0.001
 At delivery5246 (33.0%)1675 (25.3%)1619 (42.6%)1952 (35.7%)
 Postpartum 1722 (10.8%)771 (11.6%)430 (11.3%)521 (9.5%)
 Other87 (0.5%)37 (0.6%)21 (0.6%)29 (0.5%)
Maternal titer of nontreponema
 ≤1 : 411118 (70.0%)4780 (72.2%)2587 (68.1%)3751 (68.6%)<0.001
 1 : 8–1 : 323736 (23.5%)1405 (21.2%)1006 (26.5%)1325 (24.2%)
 ≥1 : 64565 (3.6%)261 (3.9%)111 (2.9%)193 (3.5%)
 Unknown465 (2.9%)173 (2.6%)94 (2.5%)198 (3.6%)
Gestational week for the first treatment
 ≤141972 (12.4%)1033 (15.6%)297 (7.8%)642 (11.7%)<0.001
 15–283151 (19.8%)1498 (22.6%)500 (13.2%)1153 (21.1%)
 29–371966 (12.4%)815 (12.3%)388 (10.2%)763 (14.0%)
 >37 or untreated8795 (55.4%)3273 (49.4%)2613 (68.8%)2909 (53.2%)
Drug of treatment
 Penicillin9386 (59.1%)3940 (59.5%)1785 (47.0%)3661 (67.0%)<0.001
 Nonpenicillin485 (3.1%)253 (3.8%)99 (2.6%)133 (2.4%)
 Untreated6013 (37.9%)2426 (36.7%)1914 (50.4%)1673 (30.6%)
Syphilis testing of husband/sexual partner
 Negative3654 (23.0%)1616 (24.4%)890 (23.4%)1148 (21.0%)<0.001
 Positive1302 (8.2%)542 (8.2%)275 (7.2%)485 (8.9%)
 Untested/unknown10928 (68.8%)4461 (67.4%)2633 (69.3%)3834 (70.1%)

Values are given as number (percentage) unless otherwise indicated.