Epidemic Profile of Maternal Syphilis in China in 2013

Table 4

Logistic regression analysis of syphilis infected pregnant women’s clinical characteristics and congenital syphilis in newborns.

	(%)	⁢Univariable		⁢Multivariable
		cOR (95% CI)	Value	aOR (95% CI)	Value
History of syphilis infection
Yes	74 (2.5%)	—		—
No	404 (3.1%)	1.23 (0.96, 1.58)	0.104	0.98 (0.76, 1.27)	0.870
Maternal syphilis stage
Latent syphilis	275 (2.6%)	—		—
Primary syphilis	38 (3.9%)	1.53 (1.09, 2.17)	0.015	1.38 (0.97, 1.96)	0.071
Secondary syphilis	8 (5.1%)	2.03 (0.99, 4.18)	0.054	1. 58 (0.76, 3.27)	0.220
Tertiary syphilis	0 (0.0%)	NA		NA
Unknown	157 (4.0%)	1.58 (1.30, 1.93)	<0.001	1.42 (1.15, 1.74)	0.001
Maternal titer of nontreponema
≤1 : 4	279 (2.5%)	—		—
1 : 8–1 : 32	150 (4.0%)	1.63 (1.33, 1.99)	<0.001	1.60 (1.30, 1.97)	<0.001
≥1 : 64	29 (5.1%)	2.10 (1.42, 3.11)	<0.001	1.90 (1.28, 2.83)	0.002
Unknown	20 (4.3%)	1.75 (1.10, 2.78)	0.018	1.37 (0.86, 2.19)	0.189
Gestational week for the first treatment
≤14	21 (1.1%)	—		—
15–28	49 (1.6%)	1.47 (0.88, 2.45)	0.144	1.41 (0.84, 2.37)	0.192
29–37	67 (3.4%)	3.28 (2.00, 5.37)	<0.001	3.20 (1.94, 5.27)	<0.001
≥37 or untreated	341 (3.9%)	3.75 (2.41, 5.84)	<0.001	3.70 (2.36, 5.80)	<0.001

The model was adjusted for maternal age, residence location, education, and job.
cOR refers to crude odds ratio.
aOR refers to adjusted odds ratio.