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BioMed Research International
Volume 2016, Article ID 9219071, 6 pages
http://dx.doi.org/10.1155/2016/9219071
Research Article

Leakage of Microbial Endotoxin through the Implant-Abutment Interface in Oral Implants: An In Vitro Study

1Department of Oral Medicine & Periodontology, School of Oral Health Sciences, Faculty of Health Science, University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
2Clinical Unit, Department of Oral Medicine & Periodontology, School of Oral Health Sciences, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa
3Malo Clinic Health and Wellness, Av. dos Combatentes 43A, 1600-042 Lisbon, Portugal
4Research and Development Department, Malo Clinics, Av. dos Combatentes 43A, 1600-042 Lisbon, Portugal
5Oral Hygiene Department, Malo Clinics, Av. dos Combatentes 43A, 1600-042 Lisbon, Portugal

Received 19 September 2016; Revised 24 November 2016; Accepted 12 December 2016

Academic Editor: Elizabeta Gjorgievska

Copyright © 2016 Rhoodie Garrana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. I. Brånemark, B. O. Hansson, R. Adell et al., “Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period,” Scandinavian Journal of Plastic and Reconstructive Surgery. Supplementum, vol. 16, pp. 1–132, 1977. View at Google Scholar · View at Scopus
  2. N. Muley, D. Prithviraj, and V. Gupta, “Evolution of external and internal implant to abutment connection,” International Journal of Oral Implantology & Clinical Research, vol. 3, no. 3, pp. 122–129, 2012. View at Google Scholar
  3. G. Niznick, “The implant abutment connection: the key to prosthetic success,” Compendium, vol. 12, no. 12, pp. 932–938, 1991. View at Google Scholar · View at Scopus
  4. G. Orsini, S. Fanali, A. Scarano, G. Petrone, S. di Silvestro, and A. Piattelli, “Tissue reactions, fluids, and bacterial infiltration in implants retrieved at autopsy: a case report,” The International Journal of Oral & Maxillofacial Implants, vol. 15, no. 2, pp. 283–286, 2000. View at Google Scholar · View at Scopus
  5. P. Proff, I. Steinmetz, T. Bayerlein, S. Dietze, J. Fanghänel, and T. Gedrange, “Bacterial colonisation of interior implant threads with and without sealing,” Folia Morphologica, vol. 65, no. 1, pp. 75–77, 2006. View at Google Scholar · View at Scopus
  6. R. Adell, U. Lekholm, B. Rockler, and P. I. Branemark, “A 15-year study of osseointegrated implants in the treatment of the edentulous jaw,” International Journal of Oral Surgery, vol. 10, no. 6, pp. 387–416, 1981. View at Publisher · View at Google Scholar · View at Scopus
  7. V. K. Jansen, G. Conrads, and E.-J. Richter, “Microbial leakage and marginal fit of the implant-abutment interface,” International Journal of Oral and Maxillofacial Implants, vol. 12, no. 4, pp. 527–540, 1997. View at Google Scholar · View at Scopus
  8. M. Tesmer, S. Wallet, T. Koutouzis, and T. Lundgren, “Bacterial colonization of the dental implant fixture-abutment interface: an in vitro study,” Journal of Periodontology, vol. 80, no. 12, pp. 1991–1997, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Harder, B. Dimaczek, Y. Açil, H. Terheyden, S. Freitag-Wolf, and M. Kern, “Molecular leakage at implant-abutment connection-in vitro investigation of tightness of internal conical implant-abutment connections against endotoxin penetration,” Clinical Oral Investigations, vol. 14, no. 4, pp. 427–432, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. G.-Q. Hou, C. Guo, G.-H. Song et al., “Lipopolysaccharide (LPS) promotes osteoclast differentiation and activation by enhancing the MAPK pathway and COX-2 expression in RAW264.7 cells,” International Journal of Molecular Medicine, vol. 32, no. 2, pp. 503–510, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. F. B. Bang, “A bacterial disease of Limulus polyphemus,” Bulletin of the Johns Hopkins Hospital, vol. 98, no. 5, pp. 325–351, 1956. View at Google Scholar
  12. A. Artiges, “Pharmacopeial standards: European pharmacopeia,” in Agnès Artiges Encyclopedia of Pharmaceutical Technology, 3rd edition, 2013. View at Google Scholar
  13. SAS Institute, SAS Version 9.3 for Windows, SAS Institute, 2011.
  14. A. Jokstad, U. Braegger, J. B. Brunski, A. B. Carr, I. Naert, and A. Wennerberg, “Quality of dental implants,” International Dental Journal, vol. 53, no. 6, pp. 409–443, 2003. View at Publisher · View at Google Scholar · View at Scopus