Aberrant LncRNA Expression Profile in a Contusion Spinal Cord Injury Mouse Model

Figure 3

STC analysis for differential expression LncRNAs related to SCI. (a) The expression patterns of these differential expression LncRNAs were analyzed and eighty model profiles were employed for epitomization. Each coordinate axis represents an expression pattern. Each expression pattern corresponds to the trend of different LncRNAs transient expression. The red line in coordinate axis has statistical significance (adj_ value < 0.05) and the blue line does not. The upper number in the coordinate axis is the number of expression profiles and value. The horizontal axis stands for the point in time after injury, and the vertical axis represents the LncRNAs expression level. The number of vertical axes does not represent the actual value of LncRNAs expression but the marker of gene expression level. (b and c) Two typical significant profiles were chosen to exhibit the specific pattern of gene expression. The curve showed individual gene expression profiles. The upper number in the coordinate axis first is the number of profile; genes_assigned represents the number of actual differential expression genes in this trend; genes_expected stands for the theoretical number of LncRNAs in this trend according to the random distribution; adj_ value represents the significant level of the ratio of the actual LncRNAs number to the theoretical number of genes in this trend. We defined the significance at adj_ value < 0.05.

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