MicroRNA-21 Promotes Proliferation of Fibroblast-Like Synoviocytes through Mediation of NF-κB Nuclear Translocation in a Rat Model of Collagen-Induced Rheumatoid Arthritis

Figure 2

The effects of downregulated miR-21 on nucleoprotein NF-κB level and cell viability. (a) The miR-21 levels in RA FLS after anti-miR-21 treatment. (b) The determination of nucleoprotein NF-κB levels using western blotting methods. (c) The change in the RA FLS proliferation rate after anti-miR-21 treatment. (d) The nucleoprotein NF-κB level after BAY 11-7082 treatment in RA FLS. (e) The change in the FLS proliferation rate after BAY 11-7082 treatment in RA FLS. . The results were statistically significant.

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