Danggui Buxue Tang Attenuates Tubulointerstitial Fibrosis via Suppressing NLRP3 Inflammasome in a Rat Model of Unilateral Ureteral Obstruction

Figure 3

Tubulointerstitial injury index, renal interstitial score, and relative expression of Col I in the obstructive kidneys. UUO group exhibited a significant increasing in tubulointerstitial injury index (a), interstitial fibrosis score (b), and staining positive area of Col I (c). Treatment with DBT and enalapril attenuated all the scores. Tubulointerstitial injury index, interstitial fibrosis score, and the staining positive area of Col I were all lower in DBT group than in enalapril-treated group. All data were presented as means ± SD, ( versus sham group; versus UUO group; and versus enalapril group).

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