Review Article
Genetic Association of CHAT rs3810950 and rs2177369 Polymorphisms with the Risk of Alzheimer’s Disease: A Meta-Analysis
Table 4
Risk of Alzheimer’s disease associated with CHAT rs3810950 polymorphism by ApoE-ε4 status.
| Genetic comparison | Non-ApoE-ε4 carriers | ApoE-ε4 carriers | Cases | Controls | OR (95% CI) | | Cases | Controls | OR (95% CI) | |
| GG + GA | 851 | 1605 | 1 (reference) | NA | 862 | 377 | 3.46 (1.78–6.71) | <0.001 | AA | 292 | 673 | 1.03 (0.62–1.71) | 0.08 | 203 | 185 | 4.87 (1.67–14.22) | 0.004 |
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Note: NA: not applicable.
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