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BioMed Research International
Volume 2016, Article ID 9498604, 7 pages
http://dx.doi.org/10.1155/2016/9498604
Research Article

Efficacy and Safety of a Permethrin-Fipronil Spot-On Solution (Effitix®) in Dogs Naturally Infested by Ticks in Europe

1Virbac, 13ème rue, LID, 06511 Carros, France
2Nadege Savelli EIRL, 2 rue de l’Église, 06270 Villeneuve-Loubet, France

Received 5 April 2016; Accepted 24 August 2016

Academic Editor: Mehmet Fatih Aydin

Copyright © 2016 Christelle Navarro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Harrus and G. Baneth, “Drivers for the emergence and re-emergence of vector-borne protozoal and bacterial diseases,” International Journal for Parasitology, vol. 35, no. 11-12, pp. 1309–1318, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. ESCCAP, “Control of vector-borne disease in dogs and cats,” in ESCCAP Guideline 05, 2nd edition, 2012. View at Google Scholar
  3. N. Mencke, “Future challenges for parasitology: vector control and ‘One health’ in Europe: the veterinary medicinal view on CVBDs such as tick borreliosis, rickettsiosis and canine leishmaniosis,” Veterinary Parasitology, vol. 195, no. 3-4, pp. 256–271, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Maia, B. Almeida, M. Coimbra et al., “Bacterial and protozoal agents of canine vector-borne diseases in the blood of domestic and stray dogs from southern Portugal,” Parasites and Vectors, vol. 8, article 138, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Otranto, F. Dantas-Torres, and E. B. Breitschwerdt, “Managing canine vector-borne diseases of zoonotic concern: part one,” Trends in Parasitology, vol. 25, no. 4, pp. 157–163, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. S. E. Little, “Future challenges for parasitology: vector control and one health in the Americas,” Veterinary Parasitology, vol. 195, no. 3-4, pp. 249–255, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. G. Baneth, P. Bourdeau, G. Bourdoiseau et al., “Vector-borne diseases—constant challenge for practicing veterinarians: recommendations from the CVBD World Forum,” Parasites & Vectors, vol. 5, no. 1, article 55, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. J.-M. R. Postal, P. C. Jeannin, and P.-J. Consalvi, “Field efficacy of a mechanical pump spray formulation containing 0.25% fipronil in the treatment and control of flea infestation and associated dermatological signs in dogs and cats,” Veterinary Dermatology, vol. 6, no. 3, pp. 153–158, 1995. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Bonneau, S. Gupta, and M.-C. Cadiergues, “Comparative efficacy of two fipronil spot-on formulations against experimental tick infestations (Ixodes ricinus) in dogs,” Parasitology Research, vol. 107, no. 3, pp. 735–739, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. M. P. Vulpiani, L. Iannetti, D. Paganico, F. Iannino, and N. Ferri, “Methods of control of the Leishmania infantum dog reservoir: state of the art,” Veterinary Medicine International, vol. 2011, Article ID 215964, 13 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Mercier, P. Jasmin, and A. Sanquer, “Prevention of sand fly attack by topical application of a permethrin/pyriproxyfen combination on dogs,” Veterinary Therapeutics, vol. 4, no. 3, pp. 309–316, 2003. View at Google Scholar · View at Scopus
  12. R. Molina, C. Espinosa-Góngora, R. Gálvez et al., “Efficacy of 65% permethrin applied to dogs as a spot-on against Phlebotomus perniciosus,” Veterinary Parasitology, vol. 187, no. 3-4, pp. 529–533, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. R. G. Endris, M. D. Matthewson, M. D. Cooke, and D. Amodie, “Repellency and efficacy of 65% permethrin and 9.7% fipronil against Ixodes ricinus,” Veterinary Therapeutics, vol. 1, no. 3, pp. 159–168, 2000. View at Google Scholar · View at Scopus
  14. R. G. Endris, D. Cooke, D. Amodie, D. L. Sweeney, and T. L. Katz, “Repellency and efficacy of 65% permethrin and selamectin spot-on formulations against lxodes ricinus ticks on dogs,” Veterinary Therapeutics, vol. 3, pp. 64–71, 2002. View at Google Scholar
  15. F. Beugnet and M. Franc, “Insecticide and acaricide molecules and/or combinations to prevent pet infestation by ectoparasites,” Trends in Parasitology, vol. 28, no. 7, pp. 267–279, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. CVMP, Guideline 9: Guideline on Good Clinical Practices, CVMP/VICH/595/98-Final, 2000.
  17. EMEA, “Guideline for the testing and evaluation of the efficacy of antiparasitic substances for the treatment and prevention of tick and flea infestation in dogs and cats,” in EMEA/CVNP/EWP/005/2000-Rev.2, 2007. View at Google Scholar
  18. European Commission, 2011—Guidelines on Pharmacovigilance for Medicinal Products for Veterinary Use, vol. 9 of The Rules Governing Medicinal Products in the European Union, 2011.
  19. EMEA, “Guideline on harmonising the approach to causality assessment for adverse reactions to veterinary medicinal products,” Tech. Rep. EMEA/CVNP/552/03-FINAL, 2004. View at Google Scholar
  20. F. Beugnet and K. Chalvet-Monfray, “Impact of climate change in the epidemiology of vector-borne diseases in domestic carnivores,” Comparative Immunology, Microbiology and Infectious Diseases, vol. 36, no. 6, pp. 559–566, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Prudhomme, N. Rahola, C. Toty et al., “Ecology and spatiotemporal dynamics of sandflies in the Mediterranean Languedoc region (Roquedur area, Gard, France),” Parasites & Vectors, vol. 8, no. 1, article 642, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Hamel, C. Silaghi, and K. Pfister, “Arthropod-borne infections in travelled dogs in Europe,” Parasite, vol. 20, no. 1, article 9, 5 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. F. Beugnet and M. Franc, “Results of a European multicentric field efficacy study of fipronil-(S) methoprene combination on flea infestation of dogs and cats during 2009 summer,” Parasite, vol. 17, no. 4, pp. 337–342, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. J.-P. Dedet, B. Carme, N. Desbois, G. Bourdoiseau, L. Lachaud, and F. Pratlong, “Epidemiology of autochthonous leishmaniases in France,” La Presse Médicale, vol. 42, no. 11, pp. 1469–1481, 2013. View at Publisher · View at Google Scholar · View at Scopus
  25. M. G. Pennisi, “Leishmaniosis of companion animals in Europe: an update,” Veterinary Parasitology, vol. 208, no. 1-2, pp. 35–47, 2015. View at Publisher · View at Google Scholar · View at Scopus
  26. B. Davoust, C. Roqueplo, D. Parzy, S. Watier-Grillot, and J.-L. Marié, “A twenty-year follow-up of canine leishmaniosis in three military kennels in southeastern France,” Parasites and Vectors, vol. 6, no. 1, article 323, 2013. View at Publisher · View at Google Scholar · View at Scopus
  27. F. Dantas-Torres, “Biology and ecology of the brown dog tick, Rhipicephalus sanguineus,” Parasites & Vectors, vol. 3, no. 1, article 26, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. F. Dantas-Torres, M. S. Latrofa, G. Annoscia, A. Giannelli, A. Parisi, and D. Otranto, “Morphological and genetic diversity of Rhipicephalus sanguineus sensu lato from the New and Old Worlds,” Parasites & Vectors, vol. 6, no. 1, article 213, 2013. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Dantas-Torres and D. Otranto, “Further thoughts on the taxonomy and vector role of Rhipicephalus sanguineus group ticks,” Veterinary Parasitology, vol. 208, no. 1-2, pp. 9–13, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. S. Nava, A. Estrada-Peña, T. Petney et al., “The taxonomic status of Rhipicephalus sanguineus (Latreille, 1806),” Veterinary Parasitology, vol. 208, no. 1-2, pp. 2–8, 2015. View at Publisher · View at Google Scholar · View at Scopus