First Observation of Leptospira interrogans in the Lungs of Rattus norvegicus

Figure 1

Immunohistochemical examination of the kidney and lungs of wild rats naturally infected with Leptospira. (a, c) Pulmonary sections obtained from two rats, DTO14 and DTO16, which were not incubated with anti-leptospire antibodies (negative control; no stain fixation). (b, d) Pulmonary sections obtained from the same rats showing the presence of leptospires (arrows) on the bronchial epithelium using anti-leptospire antibodies. (e, f) Renal sections obtained from two rats, DTO14 and DTO16, showing dense Leptospira colonization in the renal tubules using anti-leptospire antibodies (arrows).

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