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BioMed Research International
Volume 2016 (2016), Article ID 9705287, 9 pages
Clinical Study

High Intensity Resistance Training Methods with and without Protein Supplementation to Fight Cardiometabolic Risk in Middle-Aged Males: A Randomized Controlled Trial

1Institute of Medical Physics, University of Erlangen-Nürnberg, Henkestrasse 91, 91052 Erlangen, Germany
2Department of Sports Science, University of Kaiserslautern, Erwin-Schrödinger-Straße, 67663 Kaiserslautern, Germany

Received 24 October 2015; Revised 17 December 2015; Accepted 20 December 2015

Academic Editor: Danilo S. Bocalini

Copyright © 2016 Wolfgang Kemmler et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Time-effective protocols may potentially increase people’s compliance with exercise. The purpose of this paper was to compare the relative effects of 16 weeks of high intensity (resistance) training (HIT) with and without protein supplementation (HIT&P) and HVHIT (high volume/high intensity training) versus a nontraining control group on cardiometabolic risk factors. One hundred and twenty untrained males 30–50 years old were randomly assigned to 3 subgroups: (a) a HIT group; (b) a HIT&P group, and (c) a waiting-control group (phase I) that crossed over to (d) high volume/high intensity training (HVHIT) during the second study phase. HIT was defined as “single set to failure protocol” while HVHIT consistently applied two sets. Protein supplementation provided an overall intake of 1.5 g/kg/body mass. Primary study endpoint was the metabolic syndrome -Score (MetS--Score). MetS--Score significantly improved in all exercise groups () with no significant difference between HIT, HIT&P, and HVHIT (). However, all the exercise groups differed significantly from the CG () which deteriorated significantly (). In conclusion, all exercise protocols were similarly effective in improving cardiometabolic risk factors. Thus, HIT may be the best choice for people with low time budgets looking to improve their cardiometabolic health.