Research Article
Circulating Endocannabinoids and Insulin Resistance in Patients with Obstructive Sleep Apnea
Table 2
Clinical and biochemical characteristics of OSA patients.
| | Measurement | Mild OSA () | Moderate OSA () | Severe OSA () | value |
| | Age (years) | 55.3 ± 9.3 | 52.5 ± 8.3 | 56.5 ± 7.5 | >0.05 | | Women/men | 6/12 | 8/16 | 8/12 | >0.05 | | BMI (kg/m2) | 26.2 ± 2.2 | 27.2 ± 2.7 | 29.3 ± 4.6 | <0.05 | | Waist circumference (cm) | 90.0 ± 3.9 | 90.9 ± 3.9 | 90.9 ± 4.3 | >0.05 | | TC (mmol/L) | 4.46 ± 0.60 | 4.91 ± 0.6 | 5.35 ± 0.67 | <0.05 | | LDL-C (mmol/L) | 2.98 ± 0.41 | 3.27 ± 0.37 | 3.36 ± 0.25 | <0.05 | | HDL-C (mmol/L) | 1.17 ± 0.10 | 1.15 ± 0.17 | 1.04 ± 0.24 | <0.05 | | TGs (mmol/L) | 2.15 ± 0.24 | 2.22 ± 0.30 | 2.15 ± 0.29 | >0.05 | | AHI (events/h) | 11.5 ± 2.4 | 20.8 ± 3.7 | 46.7 ± 13.8 | <0.01 | | Mean oxygen saturation (%) | 92.4 ± 1.5 | 89.9 ± 2.6 | 87.5 ± 3.4 | <0.01 | | Lowest oxygen saturation (%) | 80.2 ± 5.6 | 75.7 ± 5.0 | 65.4 ± 6.9 | <0.01 | | Oxygen saturation < 90% (%) | 20.9 ± 3.9 | 22.8 ± 3.9 | 26.0 ± 4.9 | <0.01 | | Fasting glucose (mmol/L) | 5.36 ± 0.79 | 5.57 ± 0.99 | 5.84 ± 0.99 | >0.05 | | Fasting insulin (mlU/L) | 17.7 ± 4.5 | 22.9 ± 8.4 | 27.2 ± 6.9 | <0.01 | | HOMA-IR | 2.34 ± 0.59 | 2.94 ± 0.99 | 3.46 ± 0.77 | <0.01 | | AEA (nmol/L) | 2.65 ± 0.49 | 3.18 ± 0.62 | 3.61 ± 0.77 | <0.01 | | 1/2-AG (nmol/L) | 38.8 ± 5.3 | 40.4 ± 4.9 | 40.9 ± 6.3 | >0.05 |
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Data are presented as mean ± SD. Differences were considered significant when .
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