Endothelial Microparticles Act as Novel Diagnostic and Therapeutic Biomarkers of Diabetes and Its Complications: A Literature Review

Table 1

The role plasma EMPs play in DM.

	Animal model	Clinical study	References
EMPs in DM		Increased procoagulant activity (ex vivo)	[16]
		Faster brachial-ankle pulse-wave velocity and reduced FMD (in vivo)	[29]
		CAD (in vivo)
		Impaired angiogenesis (ex vivo)	[6, 17]
		Progression and severity of retinopathy (in vivo)	[30]
	Impaired cerebral microvascular density and impaired EPC functions (in vivo and ex vivo)		[18]