Protective Effect of an Antibody against Specific Extracellular Domain of TLR2 on Agonists-Driven Inflammatory and Allergic Response

Figure 3

Inhibition of anti-T20 on PGN, LTA and Pam3CSK4-driven TNF-α and IL-6 secretion by RAW264.7 cells. The production of TNF-α and IL-6 by RAW264.7 cells stimulated with (a) PGN, (b) LTA, and (c) Pam3CSK4 in the presence or absence of anti-T20. Supernatants were collected separately from each of the respective groups, and detecting TNF-α and IL-6 levels by commercial ELISA kits as described in Section 2. Data are the mean ± SD of triplicates from an experiment that was repeated three times with similar results. , , and versus control.

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