Protective Effect of an Antibody against Specific Extracellular Domain of TLR2 on Agonists-Driven Inflammatory and Allergic Response

Figure 4

Effects of anti-T20 on PGN- challenged OVA allergic mice in vivo. (a) The rectal temperature, (b) the survival rate, and (c) the outward appearance of OVA allergic mice (OVA model), OVA allergic plus r-anti-T20 mice (OVA model + anti-T20), OVA allergic plus PGN challenge mice (OVA model + PGN), OVA allergic plus PGN challenge plus rabbit-anti-T20 mice (OVA model + PGN + r-anti-T20), OVA allergic plus PGN challenge plus rabbit IgG isotype control mice (OVA model + PGN + rIgG), and normal mice as described in Section 2 (). Changes in rectal temperature and mortality were determined, respectively.

(a)

(b)

(c)