Sodium Tanshinone IIA Sulfonate Attenuates Scopolamine-Induced Cognitive Dysfunctions via Improving Cholinergic System

Figure 4

Effect of STS on the oxidative stress status in SCOP-treated mice. The supernatant of hippocampus homogenate was used for the assay of (a) ROS and (b) MDA levels and (c) SOD activity. The supernatant of cortex homogenate was used for the assay of (d) ROS and (e) MDA levels and (f) SOD activity. Data represent mean ± SEM ( per group). CON: vehicle control; SCOP: scopolamine; STSL: scopolamine + STS (10 mg/kg); STSH: scopolamine + STS (20 mg/kg); DON: scopolamine + Donepezil. versus vehicle control group; versus SCOP-treated group.

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