MicroRNA Expression Varies according to Glucose Tolerance, Measurement Platform, and Biological Source
Table 1
Clinical parameters of study participants.
T2D
IGT
NGT
4
4
4
Age (years)
46.8 ± 6.6
47.3 ± 6.9
46.3 ± 5.7
Gender
Female
Female
Female
Ethnicity
Mixed ancestry
Mixed ancestry
Mixed ancestry
BMI (kg/m2)
36.7 ± 3.1
38.6 ± 3.7
33.7 ± 1.8
2 hr OGTT (mmol l−1)
13.4 ± 0.7
8.9 ± 0.3
5.6 ± 0.3
FPG (mmol l−1)
6.7 ± 0.5
5.4 ± 0.3
5.1 ± 0.1
HbA1c (%)
6.5 ± 0.2
5.6 ± 0.2
5.4 ± 0.07
Blood pressure (mmHg):
Systolic
113.7 ± 10.8
131.3 ± 5.9
118.5 ± 4.0
Diastolic
72.3 ± 8.7
83.3 ± 4.4
82.0 ± 3.4
Fasting insulin (ng ml−1)
23.6 ± 6.7
34.8 ± 6.3
21.6 ± 3.1
2 hr insulin (ng ml−1)
97.8 ± 28.4
264.4 ± 87.7
92.5 ± 23.7
Fasting C-peptide (ng ml−1)
2.7 ± 0.6
2.9 ± 0.4
2.7 ± 0.2
2 hr C-peptide (ng ml−1)
7.9 ± 1.8
11.1 ± 1.7
9.1 ± 0.8
Glucagon (pg ml−1)
91.0 ± 9.5
114.2 ± 16.9
79.6 ± 6.6
Cholesterol (mmol l−1)
5.5 ± 0.7
5.3 ± 0.3
5.4 ± 0.8
HDL (mmol l−1)
1.2 ± 0.1
1.2 ± 0.1
1.3 ± 0.03
LDL (mmol l−1)
3.8 ± 0.6
3.6 ± 0.3
3.6 ± 0.7
Triglycerides (mmol l−1)
1.2 ± 0.3
1.7 ± 0.3
1.1 ± 0.2
= number of participants; BMI = body mass index; FPG = fasting plasma glucose; OGTT = oral glucose tolerance test; HbA1c = glycated haemoglobin A1c; 2 hr refers to a test performed 2 hrs after an oral glucose challenge. HDL = high-density lipoprotein; LDL = low-density lipoprotein. ; ; .
