Preoperative Antihypertensive Medication in Relation to Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Meta-Analysis

Table 3

Subgroup analysis between preoperative hypertension and POAF.

Variable	Number of studies	RR (95% CI)		Effects models	value
Different region
Asia	4	1.03 (0.97–1.09)	32	Fixed effects models	0.32
Europe	12	1.08 (1.04–1.12)	53	Random effects models	<0.0001
America	7	1.07 (1.04–1.11)	61	Random effects models	<0.00001
Oceania	2	1.10 (1.00–1.21)	87	Random effects models	0.05
Study design
Case-control	14	1.06 (1.05–1.07)	0	Fixed effects models	<0.00001
Cohort	11	1.11 (1.05–1.17)	61	Random effects models	0.0002
Study quality score
NOS ≥ 6	20	1.07 (1.05–1.09)	57	Random effects models	<0.00001
NOS < 6	5	1.13 (1.01–1.26)	25	Fixed effects models	0.03
Style of operation
CABG	17	1.07 (1.05–1.09)	53	Random effects models	<0.00001
AVR	3	1.13 (1.07–1.20)	23	Fixed effects models	<0.0001