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BioMed Research International
Volume 2017, Article ID 1262108, 8 pages
Clinical Study

AQUACEL® Ag Surgical Dressing Reduces Surgical Site Infection and Improves Patient Satisfaction in Minimally Invasive Total Knee Arthroplasty: A Prospective, Randomized, Controlled Study

1Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Kaohsiung, Taiwan
2Institution of Public Health, National Yang-Ming University, Taipei, Taiwan

Correspondence should be addressed to Jun-Wen Wang; wt.gro.hmgc.mda@wjgnaw

Received 11 April 2017; Revised 6 June 2017; Accepted 28 June 2017; Published 2 August 2017

Academic Editor: Paul M. Tulkens

Copyright © 2017 Feng-Chih Kuo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The use of modern surgical dressings to prevent wound complications and surgical site infection (SSI) after minimally invasive total knee arthroplasty (MIS-TKA) is lacking. In a prospective, randomized, controlled study, 240 patients were randomized to receive either AQUACEL Ag Surgical dressing (study group) or a standard dressing (control group) after MIS-TKA. The primary outcome was wound complication (SSI and blister). The secondary outcomes were wear time and number of dressing changes in the hospital and patient satisfaction (pain, comfort, and ease of use). In the intention-to-treat analysis, there was a significant reduction in the incidence of superficial SSI (0.8%, 95% CI 0.00–2.48) in the study group compared to 8.3% (95% CI 3.32–13.3) in the control group (). There were no differences in blister and deep/organ-space SSIs between the two groups. Multivariate analysis revealed that AQUACEL Ag Surgical dressing was an independent risk factor for reduction of SSI (odds ratio: 0.07, 95% CI: 0.01–0.58, ). The study group had longer wear time ( versus days, ) and lower number of dressing changes ( versus times, ). Increased patient satisfaction () was also noted in the study group. AQUACEL Ag Surgical dressing is an ideal dressing to provide wound care efficacy, patient satisfaction, reduction of SSI, and cost-effectiveness following MIS-TKA.