Pentoxifylline Regulates Plasminogen Activator Inhibitor-1 Expression and Protein Kinase A Phosphorylation in Radiation-Induced Lung Fibrosis

Figure 5

Western analysis of PAI-1 signaling related proteins in lung epithelial cells. (a–c) Western analysis of FN and PAI-1 expression (a), TGF-β/Smad3 (b), and PKA (c) in BEAS-2B cells at 120 hours after irradiation. Band densities were normalized to those of β-actin. Values are expressed relative to control and are the mean ± SEM. versus control group; versus IR group. Each experiment was repeated at least three times.

(a)

(b)

(c)