Drug Target Protein-Protein Interaction Networks: A Systematic Perspective

Figure 3

Distribution of eigenvector centrality. Drug targets and other proteins have the same distribution of the eigenvector centrality. The inset shows that the amount of changes on the eigenvector centrality after removing the drug targets is negligible. But the average eigenvector centrality of drug targets is not lower than others although the results of the analysis on degree and betweenness implied the drug targets are not the hubs.