Research Article
Drug Target Protein-Protein Interaction Networks: A Systematic Perspective
Table 2
The results of the experiments (10-fold cross-validation).
| | Algorithm | Using all features
(8 topological features) | Using particular characteristics
(3 topological features) | | Accuracy | Positive predictive value | Negative predictive value | Accuracy | Positive predictive value | Negative predictive value |
| | C4.5 | 65.2% | 63.4% | 66.5% | 68.7% | 67.7% | 69.5% | | Logistic regression | 54.2% | 52.8% | 56.0% | 67.6% | 63.4% | 68.0% | | Naive Bayes | 56.8% | 54.4% | 58.2% | 67.3% | 64.9% | 68.0% | | Bayes network | 64.5% | 63.4% | 65.0% | 70.6% | 67.3% | 71.5% | | SVM | 65.8% | 60.2% | 67.4% | 72.0% | 69.7% | 73.4% | | Radom forest | 63.2% | 60.4% | 65.5% | 69.6% | 66.4% | 70.5% |
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