Postmenopausal Iron Overload Exacerbated Bone Loss by Promoting the Degradation of Type I Collagen

Figure 4

Correlation between serum iron and degradation of type I collagen. There was no correlation between serum iron, ALP, and TRACP. Elevated ALP and TRACP were not caused by iron overload. However, PINP and β-CTX levels were both positively correlated with iron levels (). Iron overload promoted the degradation of type I collagen.