High Glucose Promotes CD36 Expression by Upregulating Peroxisome Proliferator-Activated Receptor γ Levels to Exacerbate Lipid Deposition in Renal Tubular Cells

Figure 5

Regulation of HK-2 cell viability by CD36siRNA, LY294002, RSG, or GW9662 under NG and HG conditions. The HK-2 cells were incubated with NG (5.6 mM), NG + NTCsiRNA, NG + CD36siRNA, NG + LY294002 (15 uM), NG + RSG (5 uM), NG + GW9662 (2.5 uM), HG (30 mM), HG + NTCsiRNA, HG + CD36siRNA, HG + LY294002 (15 uM), HG + RSG (5 uM), or HG + GW9662 (2.5 uM) for 48 h. Cell viability was determined by using CCK-8 assay. Data from three independent experiments were expressed as means ± SD. versus NG; versus HG.