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BioMed Research International
Volume 2017, Article ID 1419676, 11 pages
https://doi.org/10.1155/2017/1419676
Research Article

A Study of 358 Cases of Locally Advanced Nasopharyngeal Carcinoma Receiving Intensity-Modulated Radiation Therapy: Improving the Seventh Edition of the American Joint Committee on Cancer T-Staging System

Department of Oncology, Xiangya Hospital, Central South University, No. 87, Xiangya Road, Changsha, Hunan Province 410008, China

Correspondence should be addressed to Liangfang Shen; moc.361@gnafgnailnehs

Received 20 September 2016; Revised 30 November 2016; Accepted 28 December 2016; Published 7 February 2017

Academic Editor: Charnita M. Zeigler-Johnson

Copyright © 2017 Qin Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table1. After adjusted by some factors mentioned in the text, multivariate analysis found that the T category of the 7th AJCC edition was not an independent prognostic factor for OS (HR = 1.707, 95% CI, 0.732–3.981; P = 0.216), LRFS (HR = 1.341, 95% CI, 0.302–5.943, P = 0.700), DMFS (HR = 2.606, 95% CI, 0.940–7.225, P = 0.066) and DFS (HR = 2.041, 95% CI, 0.938–4.441 , P = 0.072). Table 2. Multivariate analysis of anatomical sites found that paranasal sinus involvement was an independent factor affecting OS (P =0.011), LRFS (P =0.011), DMFS and DFS (P <0.01). And cavernous sinus invasion was an independent factor affecting overall survival (HR = 1.886, 95% CI, 1.097–3.242, P = 0.022).

  1. Supplementary Material