A Study of 358 Cases of Locally Advanced Nasopharyngeal Carcinoma Receiving Intensity-Modulated Radiation Therapy: Improving the Seventh Edition of the American Joint Committee on Cancer T-Staging System

Table 1

Characteristics of the 358 patients treated with IMRT.

Variable	AJCC7; T3; ()	T4; ()	value
Age
50	46	186	0.191
≥50	18	108
Gender
Female	16	87	0.462
Male	48	207
N stage
N0	14	52	0.299
N1	20	93
N2	24	94
N3	6	55
Histologic type
Poorly differentiated SCC	58	275	0.407
Well-differentiated SCC	6	19
Tumor volume
≤46.4 mL	60	159	0.000
46.4 mL	4	135
Chemotherapy
None	3	18	0.315
Concurrent or NACT or adjuvant	14	34
Concurrent + NACT	8	31
Concurrent + adjuvant	1	9
NACT + adjuvant	14	78
NACT + concurrent + adjuvant	25	124
Prescribed total dose
<73.92 Gy	57	265	0.819
≥73.92 Gy	7	29

SCC, squamous cell carcinoma; NACT, neoadjuvant chemotherapy.