Table 3: Statistical comparison of microorganism frequency (prevalence), colonisation, and growth intensity between CLP group and CSP group at T2.

MicroorganismCLP group ()pCSP group ()
(%) Colonisation (%)GI (%) Colonisation (%)GI

Streptococcus mitis1006010030.00256641003
Streptococcus oralis 1010010030.103
Streptococcus pneumoniae13.310010030.77716.01001003
Streptococcus sanguinis5010046.630.45840.0100603
Streptococcus salivarius1005010030.02284.047.61003
Streptococcus vestibularis10.066.610030.103
Streptococcus bovis biovar I13.3505030.17428.010085,73
Streptococcus acidominimus13,35010030.17428.01000.03
Streptococcus agalactiae6.610010030.26416.0100503
Streptococcus pyogenes13.310010030.058
Streptococcus uberis6.610010030.48712.01001003
Streptococcus anginosus13.35010020.058
Streptococcus intermedius26.610010030.34316.010085.73
Lactobacillus spp.13.37510030.058
Gemella haemolysans26.662.510020.17712.01001003
Enterococcus spp.13.375.010030.88512.010066.63
Staphylococcus aureus MSSA93.371.464.23<0.00120.0801003
Staphylococcus epidermidis83.392.01002<0.00128.071.457.13
Staphylococcus hominis13.310010010.058
Lactococcus lactis13.31000.030.058
Neisseria spp.53.356.293.730.69548.083.366.63
Enterobacter cloacae36.690.910020.007
Enterobacter kobei26.610010030.053
Enterobacter aerogenes13.3507520.058
Hafnia alvei3.310010020.359
Klebsiella pneumoniae53.387.51003<0.001
Klebsiella oxytoca76.643.456.53<0.001
Escherichia coli36.610010020.31124.010083.32
Candida albicans6.610010020.190

, frequency, that is, percentage (%) of subjects from CLP group or CSP group with a given microorganism; colonisation, percentage (%) of smears of a given bacterial species from the palate and/or from the tongue; A1, smears were obtained from palatal mucosa on the cleft margin in CLP subjects; A2, smears were obtained from the dorsum of the tongue in CLP subjects; B1, smears were obtained from the palatal mucosa in CSP subjects; B2, smears were obtained from the dorsum of the tongue in CSP subjects; GI, growth intensity; -square test; results printed in boldface have reached statistical significance (p < 0.05).