Chenodeoxycholic Acid Derivative HS-1200 Inhibits Hepatocarcinogenesis and Improves Liver Function in Diethylnitrosamine-Exposed Rats by Downregulating MTH1

Figure 1

Liver function of HS-1200 toxicity assessment groups. (a) Serum ALT; (b) serum AST; (c) serum GGT; (d) serum ALB. Data expressed as mean ± SD. versus control. ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, transpeptidase; ALB, albumin. HS-1200, N-[(3a,5b,7a)-3,7-dihydroxy-24-oxocholan-24-yl] b-alanine benzyl ester.

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