Research Article

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling

Table 1

Curcumin protects against the progression of diabetic nephropathy in db/db mice.

db/mdb/dbdb/db + Cur

Body weight, g
Kidney weight, g
Blood glucose, mmol/L
SCR, μmol/L
BUN, mmol/L
Urinary albumin, μg/24 h

db/m, nondiabetic mice; db/db, diabetic mice (mock-treated); db/db + Cur, db/db mice treated with curcumin at a dose of 200 mg/kg body weight.
, compared with the db/m mice (control); , compared with the mock-treated db/db mice ( per group).
Values shown are mean ± SD.
SCR, serum creatinine; BUN, blood urea nitrogen.