Serum Butyrylcholinesterase Activity: A Biomarker for Parkinson’s Disease and Related Dementia

Table 1

Clinical characteristics of PD patients and healthy controls.

Variable (SD/%)	PD (76)	Control (61)	value
Age (year)	69.30 ± 8.99	67.87 ± 5.74	0.260
Gender, male	45 (59.2%)	29 (47.5%)	0.173
Albumin (g/L)	38.99 ± 3.93	39.92 ± 3.52	0.152
ALT (U/L)	18.99 ± 13.58	20.03 ± 9.94	0.616
AST (U/L)	23.04 ± 13.59	20.93 ± 6.51	0.238
TC (mmol/L)	4.25 ± 0.84	4.19 ± 0.91	0.701
TG (mmol/L)	1.25 ± 0.76	1.45 ± 0.79	0.116
BMI	23.28 ± 3.36	23.71 ± 3.16	0.449
Smoking history	14 (18.2%)	20 (32.8%)	0.053
Alcohol consumption	7 (9.2%)	5 (7.8%)	0.835
CHD	15 (19.7%)	7 (10.9%)	0.191
Hypertension	29 (38.2%)	29 (47.5%)	0.269
Diabetes mellitus	10 (13.2%)	10 (16.4%)	0.594
Hypercholesterolaemia	15 (19.7%)	9 (14.8%)	0.446
BChE activity (IU/L)	6869.94 ± 1343.51	7904.29 ± 1470.77	<0.001

PD, Parkinson’s disease; SD, standard deviation; ALT, alanine transaminase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; BMI, body mass index; CHD, coronary heart disease; BChE, butyrylcholinesterase.