Serum Butyrylcholinesterase Activity: A Biomarker for Parkinson’s Disease and Related Dementia

Table 4

Univariate and multivariate linear regression analysis of correlation factors for serum butyrylcholinesterase activity in patient with Parkinson’s disease.

Variable	Univariate		Multivariate
	Beta value	value	Beta value	value
Disease duration	−0.202	0.080	/	/
Age	−0.354	0.002	—	—
Gender	0.248	0.031	0.277	0.001
Albumin	0.568	0.000	0.493	0.000
ALT	0.029	0.802	/	/
AST	−0.196	0.089	/	/
TC	0.399	0.000	—	—
TG	0.261	0.023	—	—
BMI	0.305	0.007	0.188	0.029
Smoking history	0.001	0.993	/	/
Alcohol consumption	−0.051	0.662	/	/
Hypertension	0.024	0.834	/	/
Diabetes mellitus	0.076	0.515	/	/
Hypercholesterolaemia	0.133	0.251	/	/
CHD	−0.097	0.406	/	/
Advanced stage	−0.190	0.101	/	/
Dementia	−0.360	0.001	−0.319	0.000

Beta value, adjusted regression coefficient; ALT, alanine transaminase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; BMI, body mass index; CHD, coronary heart disease; PD, Parkinson’s disease.
For the multivariate linear regression analysis using a backward method based on the results from univariate linear regression analysis, the values were “/” if variables were excluded before the analysis, and the values were “—” if variables were excluded after the analysis.