Serum Butyrylcholinesterase Activity: A Biomarker for Parkinson’s Disease and Related Dementia

Table 7

Univariate and multivariate binary logistic regression analysis of correlation factors for Parkinson’s disease related dementia.

Variable	Univariate		Multivariate
	OR (LL~UL)	value	OR (LL~UL)	value
Disease duration	1.154 (1.033~1.290)	0.011	—	—
Age	1.080 (1.006~1.159)	0.034	—	—
Gender	1.391 (0.469~4.124)	0.551	/	/
Albumin	0.936 (0.817~1.071)	0.336	/	/
ALT	1.009 (0.992~1.026)	0.302	/	/
AST	1.018 (0.991~1.046)	0.197	/	/
TC	0.680 (0.343~1.349)	0.270	/	/
TG	0.758 (0.339~1.694)	0.499	/	/
BMI	0.981 (0.834~1.154)	0.820	/	/
Smoking history	1.508 (0.406~5.593)	0.539	/	/
Alcohol consumption	2.946 (0.590~14.708)	0.188	/	/
Hypertension	0.608 (0.189~1.949)	0.402	/	/
Diabetes mellitus	0.850 (0.163~4.439)	0.847	/	/
Hypercholesterolaemia	0.472 (0.095~2.334)	0.357	/	/
CHD	3.030 (0.893~10.284)	0.075	/	/
Advanced stage	7.250 (1.522~34.543)	0.013	5.612 (1.132~27.827)	0.035
BChE activity	0.999 (0.999~1.000)	0.004	0.999 (0.999~1.000)	0.013

OR, odds ratio; LL, lower limit; UL, upper limit; ALT, alanine transaminase; AST, aspartate aminotransferase; TC, total cholesterol; TG, triglyceride; BMI, body mass index; CHD, coronary heart disease; BChE, butyrylcholinesterase.
For the multivariate binary logistic regression analysis using a conditional backward method based on the results from univariate binary logistic regression analysis, the values were “/” if variables were excluded before the analysis, and the values were “—” if variables were excluded after the analysis.