Association of Platelet Membrane Glycoprotein HPA-2a/b, GP VI T13254C, and GP Ibα VNTR Polymorphisms with Risk of Coronary Artery Disease: A Meta-Analysis

Table 3

Meta-analysis of studies examining association between GP VI T13254C, GP Ibα VNTR polymorphisms and risk of coronary artery disease.

Genotype	Number of trails	Heterogeneity		Effect model	Meta-analyses
			value		OR	95% CIs	value
GP VI T13254C allele model	8	73	<0.01	Random	1.0	0.82–1.37	0.66
GP VI T13254C dominant model	6	4	0.39	Fixed	1.1	0.93–1.31	0.24
GP Ibα VNTR A allele model	5	0	0.47	Fixed	1.1	0.70–1.91	0.58
GP Ibα VNTR B allele model	5	51	0.08	Random	1.0	0.72–1.59	0.74
GP Ibα VNTR C allele model	5	57	0.06	Random	1.0	0.80–1.32	0.86
GP Ibα VNTR D allele model	5	0	0.43	Fixed	1.1	0.93–1.32	0.25
GP Ibα VNTR A allele dominant model	5	0	0.49	Fixed	1.0	0.60–1.81	0.88
GP Ibα VNTR B allele dominant model	5	67	0.02	Random	1.2	0.70–2.20	0.46
GP Ibα VNTR C allele dominant model	5	34	0.19	Fixed	0.8	0.58–1.31	0.50
GP Ibα VNTR D allele dominant model	5	0	0.80	Fixed	1.0	0.82–1.25	0.91
GP Ibα VNTR BC codominant model	5	76	<0.01	Random	1.3	0.64–2.74	0.44
GP Ibα VNTR CC codominant model	5	58	0.05	Random	0.9	0.64–1.29	0.59