High-Density Lipoprotein Cholesterol, Blood Urea Nitrogen, and Serum Creatinine Can Predict Severe Acute Pancreatitis
Table 1
Univariate analysis of predictive factors of acute pancreatitis in 647 patients.
Characteristic
Mild AP
Moderate AP
Severe AP
value
()
()
()
Median age, years (IQR)
47 (37–62)
47.5 (40–63)
51 (38–66)
0.165
Male sex, (%)
309 (62.9)
66 (67.4)
31 (53.4)
0.219
BMI
23.4 (20.9–26.1)
24.6 (21.5–26.0)
24.2 (22.1–26.6)
0.048
Etiology
0.002
Biliary, (%)
222 (45.2)
32 (32.7)
18 (31.0)
Alcohol, (%)
63 (12.8)
23 (23.5)
4 (6.9)
Hypertriglyceridemia, (%)
22 (4.5)
7 (7.1)
7 (12.1)
Idiopathic, (%)
184 (37.5)
36 (36.7)
29 (50.0)
Laboratory findings
Hematocrit
0.42 (0.38–0.45)
0.43 (0.39–0.47)
0.44 (0.40–0.47)
0.001
HDL-C (mg/dl)
41.3 (32.0–51.0)
36.7 (25.5–51.7)
22.4 (17.8–38.2)
<0.001
BUN, mg/dl (IQR)
13.2 (10.4–16.5)
12.2 (9.8–16.5)
19.9 (15.1–31.9)
<0.001
BUN (24 h), mg/dl (IQR)
12.9 (9.5–16.8)
12.2 (9.5–19.0)
26.0 (17.1–34.5)
<0.001
Creatinine, mg/dl (IQR)
0.72 (0.61–0.86)
0.72 (0.61–0.88)
0.92 (0.66–1.82)
<0.001
Creatinine (24 h), mg/dl (IQR)
0.72 (0.59–0.86)
0.68 (0.55–0.87)
1.04 (0.74–2.34)
<0.001
BISAP score
1 (0-1)
1 (1-2)
2 (1–3)
<0.001
IQR = Interquartile Range; = number; AP = acute pancreatitis; BMI = Body Mass Index; HDL-C = High-Density Lipoprotein Cholesterol; BUN = Blood Urea Nitrogen; BISAP = Bedside Index for Severity in Acute pancreatitis.
