Research Article

PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?

Table 2

Association between stromal TILs, the expression of PD-L1 on tumor cells and inflammatory infiltrate, Ki-67 value, cT, cN, and pCR in the univariate analysis.

(%)pCR
value

Stromal TILs
 Absent/low32 (59%)8<0.001
 High22 (41%)11

PD-L1 on tumor cells
 0%35 (65%)11
 ≥1–<25%15 (28%)4
 ≥25%4 (7%)40.024

PD-L1 on inflammatory cells
 Negative10 (19%)3ns
 Positive44 (81%)15

Ki-67
 <50%14 (26%)4ns
 ≥50%40 (74%)15

cT
 T17 (13%)3ns
 T2–T447 (87%)16

cN
 Negative30 (56%)13ns
 Positive24 (44%)6