Anti-Inflammatory Effect of Dialyzable Leukocyte Extract in Autoimmune Prostatitis: Evaluation in Animal Model

Figure 4

DLE modified the expression of some proinflammatory molecules. The expression percentage was semiquantified with software Image-Pro Premier. (a) Microphotographs are in 100x. CD45 in normal tissue showed a basal expression. CD45 expression in the Dexamethasone treated group was similar to the WOT group. The DLE treated group showed a significantly lesser expression in comparison to the other groups. TNF-α in the normal group also showed a basal expression. The Dexamethasone treated group showed a TNF-α expression similar to the WOT. The DLE treated group showed a significantly lower expression than that in other groups. IFN-γ in the normal group displayed a basal expression. The placebo treated group showed a decreased IFN-γ expression in comparison with the other groups. The Dexamethasone and DLE treated groups showed an IFN-γ expression similar to normal group. IL-6 in the normal group showed a basal expression. In the Dexamethasone and DLE treated groups, the IL-6 expression was similar to the normal group. For IL-17 we did not observe any significant differences. (b) Graph of the semiquantification of the percentage of expression in all groups. “” indicates groups that showed statistical significance (), and the lines indicate groups that were compared.

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