Urethral Reconstruction Using Mesothelial Cell-Seeded Autogenous Granulation Tissue Tube: An Experimental Study in Male Rabbits

Figure 5

Gross and histological examinations of the retrieved urethra 6 months after implantation. In the seeded grafts, the mucosa appeared normal with no severe shrinkage as indicated by the marking sutures (upper). In the unseeded grafts, severe fibrosis occurred. Histological analysis showed layers of urothelium and organized smooth muscle bundles in the seeded grafts and extensive scarring of collagen fibers in the unseeded grafts (original magnification 100x).