Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Table 2

Effect of E. speciosa on “unhealed gastric ulcers” in pylorus-ligated rats treated with histamine.

Treatment	Dose (mg/kg)		Ulcerated area (mm^2)	% ulcerated area	% healing	Mucus production (mg)
Control 1	—	5	61.20 ± 3.61	9.07	—	78.68 ± 4.00
Control 2	—	5	42.50 ± 5.29	6.30	30.56	49.25 ± 2.37
E. speciosa	200	5	7.50 ± 0.39	1.11	82.35	70.00 ± 0.63
E. speciosa	400	5	6.30 ± 0.37	0.93	85.17	80.25 ± 3.77

: number of rats. The values are expressed as mean ± SEM; ; statistically different compared to Control 2. Control 1: ulcerated rats sacrificed 4 days after acetic acid ulcer induction. Control 2: ulcerated rats given indomethacin alone for 14 days following ulcer induction.